Everything You Need To Know About P-Shot Treatment For Men

February 15, 2025
Share

In recent years, P-Shot, also called Priapus Shot, has become a talked-about treatment in men's sexual health. It is marketed as a natural method to improve erection ability and increase sexual sensation. By using the body's own healing mechanisms, P-Shot is said to be able to give men harder and longer-lasting erections -- without having to take daily medications such as Viagra or Cialis.

But how well does the treatment actually work? Is there scientific evidence to support the claimed benefits, or is it mostly an expensive placebo effect? And what does the research say about the safety and possible risks?

In this blog we go over P-Shot from the ground up — what the treatment means, how it works and what effects to expect. We also review what the latest research says about its effectiveness and safety.

What is P-Shot and how does it work?

P-Shot (Priapus Shot) is an injection treatment that uses platelet-rich plasma (PRP) — platelet-rich plasma from the patient's own blood — to stimulate tissue repair and improved blood circulation in the penis. The treatment is based on the idea that platelets, which are rich in growth factors, can promote the healing and new formation of blood vessels, which in turn can improve erection ability.

How is the treatment done?

  1. A blood sample is taken from the patient, usually from the arm.
  2. The blood is centrifuged to separate platelet-rich plasma from the other blood components.
  3. The concentrated PRP solution is drawn up into a syringe and injected into specific points in the penis.
  4. After the injection, some patients are advised to use a vacuum pump to maximize blood circulation and the spread of PRP in the tissue.

What is the purpose of P-Shot?

  • Stimulate new tissue growth: PRP contains natural growth factors that can help repair damaged or aged tissue.
  • Improve blood flow: By promoting the formation of new blood vessels, P-Shot can potentially lead to better circulation in the penis, which is crucial for erection ability.
  • Increase sensation and pleasure: Some men report improved sexual sensation after treatment.

Where does P-Shot come from?

The method was developed and popularized by the American physician Dr. Charles Runels in the 2010s. He combined the technique of PRP treatment -- already used in sports medicine and skin rejuvenation -- with injections into the penis to potentially improve sexual function.

Why do some men choose the P-Shot?

P-Shot is marketed as a natural and safe method to improve sexual function because it uses the body's own healing mechanisms. Proponents of the method believe that it can help men who:

  • Has mild to moderate Erectile Dysfunction and wants to improve their natural erection ability.
  • Have Peyronie's disease (crooked/slanted penis due to scarring) and want to reduce scar tissue.
  • Experiencing decreased sexual sensation or weaker orgasms.
  • Want an alternative solution to drugs like Viagra or surgical procedures.

Despite these alleged advantages, the question remains: Is there scientific support that the P-Shot really works? In the next part, we review what the research says about the effectiveness of the treatment.

Boka P-shot i Stockholm

Scientific studies and evidence of effectiveness

P-Shot has attracted considerable interest as a possible treatment for erectile dysfunction, but the scientific evidence is still limited. Most studies in the field have been small and relatively short-lived, but there are a few controlled trials that have investigated the effect of platelet-rich plasma on sexual function.

What does the research say?

Early systematic reviews of P-Shot and PRP injections for erectile dysfunction have found that there has been insufficient data to confirm its effectiveness. Many studies have been small, with weak methodology and lack of control groups.

But in recent years, some more rigorous studies have been conducted:

  • A 2021 randomized, double-blind study tested PRP on 60 men with mild to moderate erectile dysfunction. Two injections of PRP produced a significant improvement in erection ability for 69 percent of patients after six months, compared with 27 percent in the placebo group. An average improvement of about four points on the IIEF-ED scale (an established erection index) was noted in the PRP group. No serious side effects were reported.
  • A 2022 French pilot study examined PRP injections on 15 men with vascular-related erectile dysfunction. The results showed some improvement in erection scores (the IIEF value increased by five points after one month, and some of the improvement persisted after six months). However, there was no significant improvement in the ability to perform sexual intercourse — the proportion increased only from 20 to 26.7 percent, which was not statistically assured.
  • A meta-analysis published in 2024 analyzed four randomized trials involving a total of 413 patients. This analysis found that PRP treatment produced significantly better results than placebo for erectile dysfunction. Men who received PRP had a higher likelihood of experiencing an improvement at both one and six months. Mean improvement on the IIEF scale was also higher for the PRP group.

Limitations in research

Despite these promising results, there are several limitations. The studies vary in quality and methodology, which makes it difficult to draw general conclusions. The long-term effects are unknown, as most studies have followed patients for a maximum of six to twelve months. Many studies lack placebo control or have few participants, making the results less robust. The majority of positive reports are anecdotal and come from clinics offering the P-Shot, rather than from independent researchers.

At present, P-Shot is still considered an experimental treatment and the scientific evidence is not yet strong enough to recommend it as a first-line treatment for erectile dysfunction.

What can P-Shot help with?

P-Shot is marketed as a treatment for a variety of sexual problems in men, but how much scientific support is there for these claims?

Erectile Dysfunction

The main purpose of P-Shot is to improve erection ability. PRP is said to stimulate blood flow and regenerate tissue in the swelling bodies, which could improve the strength and duration of erections.

What does the research say?

  • Studies have shown that PRP can provide moderate improvement for men with mild to moderate erectile dysfunction.
  • For severe erectile dysfunction or patients with neurological damage, the evidence is weaker.
  • Placebo effect may play a role -- many men experience some improvement shortly after treatment, but it is unclear whether this is due to PRP or psychological factors.

Peyronie's disease (crooked penis)

Peyronie's disease is caused by scarring of the penis, which can lead to painful erections and difficulty in sexual intercourse. PRP injections have been proposed as a method to reduce scarring and improve the flexibility of the tissue.

What does the research say?

  • An Italian study of 65 patients found that PRP injections reduced the curvature of the penis by an average of 17 degrees and reduced pain during erection.
  • Over half of the patients reported improved sexual function.
  • No serious adverse event was noted, but the study lacked placebo control.

While the results are promising, more well-controlled studies are needed to establish whether the P-Shot is an effective alternative to established treatments such as collagenase injections or surgery.

General sexual function and sensation

Some clinics market the P-Shot as a method to increase sex drive, sensation, and orgasm intensity.

What does the research say?

  • There are no scientific studies confirming that PRP can improve libido or orgasm ability.
  • Most reports of improved sensation are anecdotal.
  • If P-Shot improves erection, it may indirectly affect sexual pleasure, but that's no guarantee.

Premature ejaculation (premature ejaculation)

Some clinicians claim that P-Shot can help men who have problems with premature ejaculation by improving tissue volume and nerve function.

What does the research say?

  • No clinical study has shown that PRP affects ejaculation time.
  • Theoretically, an improved blood circulation and tissue regeneration could provide better muscle control, but this is speculative.
  • Treatment is not recommended as a first-line option for premature ejaculation.

Penis enlargement

One of the most controversial claims about P-Shot is that it can increase the size of the penis.

What does the research say?

  • No studies have shown that PRP permanently increases the length or circumference of the penis.
  • Some patients report a temporary swelling after injection, which can give the illusion of increased size.
  • If the P-Shot improves blood circulation, the penis may look more “stuffed”, but this is not an actual enlargement.

Several clinics advertise P-Shot as a method of penis enlargement, but scientific support is completely lacking. Anyone considering the treatment for this purpose should be skeptical.

Conclusion

  • P-Shot has shown some effect on erectile dysfunction, especially in mild to moderate disorders.
  • For Peyronie's disease, preliminary promising results exist, but more studies are needed.
  • When it comes to sexual sensation, orgasmic ability and premature ejaculation, scientific evidence is lacking.
  • Penis enlargement through P-Shot is a myth unsupported in research.

In summary, P-Shot remains an experimental treatment, and although some patients experience positive effects, more research is needed to determine its long-term effectiveness and safety.

Advantages of P-Shot

P-Shot treatment has become an attractive treatment for men seeking an alternative to traditional medical remedies for erectile dysfunction. Advocates highlight several benefits that make the treatment unique.

Natural treatment with body egg material
Because P-Shot uses platelet-rich plasma (PRP) from the patient's own blood, the treatment contains no synthetic substances or drugs. This reduces the risk of allergic reactions or rejection.

Minimally invasive and rapid intervention
The procedure involves only a blood test and a few small injections into the penis, making it far less invasive than surgical options.

Short recovery time and few side effects
Because it is a non-surgical treatment, most patients can return to their normal activities on the same day. Possible side effects, such as swelling and bruising, are usually mild and transient.

Possible potential to improve erection and sex life for some men
Studies have shown that PRP can have a positive effect on blood circulation and tissue regeneration, leading to improved erection ability and increased sensation. However, results vary between individuals.

Could be an option for men who don't respond to medications like Viagra
For men who have not had the desired effect of PDE5 inhibitors such as Viagra or Cialis, P-Shot may be another option to try. It has been particularly investigated as a solution for patients with vascular-related erectile dysfunction.

Book P-shot i Stockholm

How is the P-shot treatment done?

P-Shot treatment is carried out in several stages, from preparation to aftercare.

Consultation and preparation

Before starting treatment, a consultation is carried out in which the doctor assesses whether the P-Shot is suitable for the patient. Here, expectations, possible contraindications and the patient's medical history are discussed.

Blood test and PRP extraction

A blood sample is taken from the patient, most often from the arm. The blood is then placed in a centrifuge where it is rotated at high speed to separate the various components. The platelet-rich plasma is isolated and prepared for injection.

Local anesthesia of the penis

To minimize discomfort, an anesthetic cream is applied to the penis. In some cases, a local injection of anesthetic is also used.

Injections of PRP into the penile tissue

Once the anesthetic has worked, PRP is injected into specific areas of the penis, including the swelling bodies. Usually four to five injections are given with a fine needle. The treatment takes only a few minutes to complete.

Aftercare and recovery

After the injections, the patient can rest for a short time before he can go home. The recommendation is to avoid sexual intercourse or intense physical activity for the first 24—48 hours. Some clinics even recommend the use of a vacuum pump after treatment to improve blood flow and the spread of PRP.

How long does it take and when are the possible results noticeable?

The whole procedure usually takes between 30 and 60 minutes. Results may vary, but some men report an improvement within a few days, while for others it can take several weeks. The maximum effect is usually noticeable after one to two months, and in some cases more than one treatment is required to achieve the desired result.

Who can do the P-Shot?

P-Shot Treatment or PRP Penis Treatment is a treatment that may be topical for some men, but it is not a universal solution for everyone. Below is a review of which may be suitable candidates, as well as which ones should avoid the treatment.

Which men are suitable candidates for the treatment?

P-Shot can be considered by men who:

  • Has mild to moderate erectile dysfunction and wants to improve blood circulation and tissue health in the penis.
  • Have Peyronie's disease (scarring and curvature of the penis) and want to try a regenerative method.
  • Not given enough effect from drugs such as Viagra or Cialis.
  • Want to try a more natural method without synthetic drugs or surgery.
  • Have experienced impaired sensation or orgasm function and want to see if PRP can improve neural response.
  • Have undergone prostate surgery or have diabetes-related erectile dysfunction and are seeking additional options.

Contraindications — who should avoid the P-Shot?

The treatment is not recommended for men who:

  • Have severe erectile dysfunction in which the blood vessels or nerves are severely damaged, for example after certain surgeries or neurological diseases.
  • Have untreated hormonal problems, such as low testosterone, which in itself can cause erection problems.
  • Taking blood-thinning medications or having a blood disorder that affects clotting, which can increase the risk of bleeding or bruising from the injections.
  • Have active infection, skin disease or sores in the genital area that can increase the risk of infection.
  • Have high expectations for penis enlargement, as the research does not show that P-Shot increases the size of the penis permanently.
  • Has a strong psychological component to their erection problems, where talk therapy or medical treatment may be more effective.

Who carries out the treatment and how to choose the right clinic?

The P-Shot is usually performed by licensed physicians, such as urologists, aesthetic doctors, or sexual health specialists. It can also be performed by nurses with specialized training in PRP Treatments.

To choose a safe and serious clinic, one should:

  • Check that the therapist has a medical license and experience with PRP injections for sexual health.
  • Avoid clinics that make exaggerated claims about guaranteed results or penis enlargement.
  • Ask if they follow sterile procedures and use FDA or CE approved equipment for PRP separation.
  • Ask for previous patient cases or reviews to get an idea of the quality and results of treatment.
  • Ensure that a consultation is included before treatment, where the patient's health status and expectations are reviewed.

Risks and side effects of P-shot

Although P-Shot is generally considered a safe treatment, there are some side effects and risks to consider.

Common Mild Side Effects

After the injection, some patients may experience:

  • Pain or soreness at the injection site.
  • Swelling and redness that lasts for a few days.
  • Bruises or small discolorations on the skin.
  • Temporary numbness or an above sensation in the penis area.

These reactions are common and usually go away within a week.

Potential risks

Although serious complications are rare, there are some risks:

  • Infection at the injection site, especially if sterile procedures are not followed.
  • Scarring from repeated injections, although this appears to be less common with PRP compared to other injection-based treatments.
  • No effect — some men experience no noticeable improvement, meaning they have undergone a costly treatment with no results.
  • Possible activation of the underlying herpes virus if the patient is already carrying it, due to the inflammatory process.

What do we know about long-term side effects and safety?

Because P-Shot is a relatively new treatment, there is limited data on long-term side effects. Studies have shown that PRP is generally safe when used in medical and aesthetic fields, but the efficacy of repeated injections over many years remains unclear.

Important aspects to consider:

  • There are no reported cases of serious complications in the published studies.
  • Since PRP comes from the patient's own blood, the risk of allergic reactions or rejection is minimized.
  • Some clinics recommend that the P-Shot be repeated annually, but there are no long-term studies showing how this affects penile tissue in the long term.

In summary, P-Shot is considered a safe treatment when performed by qualified personnel, but the result is not guaranteed and research on long-term use is still lacking.

How much does P-Shot cost?

The price of P-Shot varies depending on the clinic, geographic location and whether the treatment is given as a single injection or in a series of multiple sessions. Since the treatment is experimental and not covered by health insurance or high-cost cover, the patient must pay for it himself.

Price levels in Sweden and internationally

In Sweden, the cost of an individual P-Shot treatment is usually between SEK 5,000 and SEK 15,000 per session. Some clinics offer package rates for multiple treatments, which can cost up to SEK 20,000-30,000.

Internationally, prices vary widely:

  • In the US, an individual P-Shot usually costs USD 1,000 TO USD 2,200 (approximately 10,000—24,000 kronor).
  • In the UK, prices are 800—1,500 GBP (approximately 10,500—20,000 SEK).
  • In some countries of Europe, prices may be slightly lower, but the method is still expensive and is classed as a luxury treatment.

How many treatments may be required for optimal effect?

The P-Shot is often given in a series of two to three treatments to maximize the effect. Some clinics recommend a “booster” treatment after 6—12 months. Because results vary from person to person, it can be difficult to predict how many treatments will be needed before an improvement is noticed.

Is it worth the money compared to other ED treatments?

P-Shot is an expensive treatment with uncertain results. For men who have already tried other options without success, it can be an interesting prospect. In contrast, PDE5 inhibitors (Viagra, Cialis) or vacuum pump are usually cheaper and more proven solutions. Shock wave therapy (ESWT) is another regenerative method that costs about as much as P-Shot but has more support in research.

Comparison with other treatments

P-Shot is just one of several options for treating erectile dysfunction. Below, the treatment is compared with other established methods.

PDE5 inhibitors (Viagra, Cialis)

  • Effectiveness: Proven and works for the majority of men with mild to moderate ED.
  • Advantages: Easy to use, cheaper than P-Shot, fast acting.
  • Disadvantages: Requires repeated dosing, can cause side effects such as headache and blood pressure impact.
  • Compared to P-Shot: Tablets are a more reliable solution for most people, but do not provide a long-term improvement in tissue.

Intracavernous injections (Caverject)

  • Effectiveness: Very high — can produce an erection within 5—10 minutes even with severe ED.
  • Advantages: Works when PDE5 inhibitors do not help, fast acting.
  • Disadvantages: Requires an injection before each sexual intercourse, can cause pain and fibrosis with repeated use.
  • Compared to P-Shot: Provides immediate effect but is not a long-term solution; P-Shot aims to improve erection ability over time.

Vacuum pump

  • Effectiveness: Works for most men, especially the elderly and those with vascular ED.
  • Advantages: Drug free, cheap one-time investment, safe.
  • Disadvantages: May feel clumsy to use, does not produce a natural erection.
  • Compared to P-Shot: Vacuum pump is a purely mechanical aid, while P-Shot is claimed to regenerate the tissue in the long run.

Shock wave therapy (ESWT)

  • Effectiveness: Some evidence suggests that low-frequency shock wave therapy can improve erection ability by stimulating new blood vessel formation.
  • Advantages: Non-invasive, can improve the natural erection ability.
  • Disadvantages: Requires multiple sessions, does not work for everyone.
  • Compared to P-ShotESWT has more clinical studies supporting its effectiveness, but the results are similar to P-Shot in that it works for some but not all.

Penile Implants

  • Effectiveness: Almost 100 percent -- surgical solution for men with severe ED where nothing else works.
  • Advantages: Permanent solution, guaranteed erection if necessary.
  • Disadvantages: Invasive surgical intervention, risk of complications and infection.
  • Compared to P-Shot: Penile implants are the last resort for men with severe ED, while P-Shot is a milder, experimental treatment for those with mild to moderate ED.

Which treatment is best for different types of ED?

  • Mild to moderate ED: PDE5 inhibitors, ESWT or P-Shot may be options.
  • Severe ED where Viagra doesn't work: Intracavernous injections or ESWT.
  • ED after prostate surgery or in diabetes: ESWT, P-Shot or intracavernous injections.
  • ED due to nerve damage: Penile implants may be the best solution.
  • ED with concomitant Peyronie's disease: P-Shot can be tried but collagenase injections or surgery have more evidence.

In summary, the P-Shot is a possible option for some men, but there are more proven and cost-effective options depending on the specific needs of the individual.

How often do I need to repeat the P-shot treatment?

How long does the effect of P-Shot last?

The effectiveness of P-Shot varies depending on the individual, but many clinics and studies indicate that improvements can be noticed as early as a few weeks and persist between 6—12 months. Thereafter, a gradual return to previous erection ability can occur if no further treatment is given.

Recommended treatment schedules

Most clinics recommend an initial treatment series at 2—3 sessions with approximately 4 weeks apart. For some patients, a single treatment is enough, but many get better results after more sessions.

To maintain the effect, it may be appropriate to use a maintenance treatment once a year, but there is no firm protocol and the recommendation varies by clinic and individual response.

Is there a limit to how many P-Shots you can take?

Because PRP is a body-resistant material, it is believed to be safe to repeat the treatment if necessary. However, there are no long-term studies examining the effects of repeated P-Shot over several years. If no noticeable improvement occurs after 2-3 treatments it is likely that more injections will not bring the desired effect.

It is important that each patient discuss with their therapist and follow up on the results before proceeding with more sessions.

Conclusion and final words

Summary of what the research says about the P-Shot

P-Shot has shown some promising potential, especially for men with mild to moderate erectile dysfunction. Studies have indicated that PRP can improve blood circulation and tissue regeneration, but research is still limited. The results are variable, and there is a lack of long-term data to confirm its effect in the longer term.

Is it worth testing? For which men might it be an option?

P-Shot can be an option for men who:

  • Has mild to moderate erectile dysfunction and want to improve blood flow naturally.
  • Not given enough effect from drugs such as Viagra or Cialis.
  • Has Peyronie's disease and want to try an alternative treatment to reduce scarring.
  • Want to avoid surgery or daily medications and prefer a more biological treatment.

For men with severe erectile dysfunction or underlying neurological damage, P-Shot is most likely not an effective solution.

The Importance of Having Realistic Expectations

It is important to understand that P-Shot is not a miracle cure. Some men may experience noticeable improvements, while others get no effect at all. There is also no scientific evidence that P-Shot can provide permanent penis enlargement, despite some marketing claims.

The importance of choosing the right clinic and combining treatment with healthy lifestyle changes

For best results, the patient should:

  • Choosing a certified clinic with experienced staff and transparent treatment procedures.
  • Ha ha reasonable expectations based on scientific facts, not solely marketing promises.
  • Combine treatment with healthy lifestyle changes such as regular exercise, a balanced diet and avoidance of smoking and alcohol, as these factors also affect erection ability.

Book P-shot i Stockholm
By clicking “Accept”, you consent to cookies being stored on your device to improve website navigation, analyse website usage and assist in our marketing efforts. To read more about our cookie policy, click here.